[Taxacom] Surprise from a whole-genome study - more pepper in the soup

[Vitor Fernandes O. de Miranda]

Hi John,

I remember a paper that authors, after producing some few sequences to
several taxa, applied basically the similarity to figure out HGT. But do not
remember have noticed any explicit method to corroborate or even verify its
likelihood. If someone knows one, I would really appreciate having it!

I guess that each case is a case. In my opinion, as safer the method as more
sampled was the genome. Comparative analyses of whole genomes are safer than
applying the HGT hypothesis only with few sequences on hands. After some
rounds (replicates) when producing a genome, if one found some "strange"
sequences in all or most replicates, it's unlikely to thank simply by
contamination. But of course each case is a case.

Attached is a very curious paper. It's postulated a fifth principle to the
Modern Synthesis including the HGT idea :-)

Best,
Vitor.

_______________________________
Prof.Dr. Vítor Fernandes Oliveira de Miranda
Universidade Estadual Paulista – UNESP
Campus Jaboticabal
Departamento de Biologia Aplicada à Agropecuária
Faculdade de Ciências Agrárias e Veterinárias – FCAV
Via de Acesso Prof. Paulo Donato Castellane s/n
CEP 14884-900     Jaboticabal – SP
Fone: +55 (16) 3209-2620  Ramal 213
email: vmiranda at fcav.unesp.br   Skype: vmirandum



-----Mensagem original-----
De: taxacom-bounces at mailman.nhm.ku.edu
[mailto:taxacom-bounces at mailman.nhm.ku.edu] Em nome de John Grehan
Enviada em: terça-feira, 26 de outubro de 2010 17:12
Para: taxacom at mailman.nhm.ku.edu
Assunto: Re: [Taxacom] Surprise from a whole-genome study

I guess it's the specifics of these that need to be explained to me.
Maybe there is a paper out there that presents the evidence for how such
sequences are recognized as viral derivatives rather than convergences.
I would be interested. John

-----Original Message-----
From: taxacom-bounces at mailman.nhm.ku.edu
[mailto:taxacom-bounces at mailman.nhm.ku.edu] On Behalf Of Sergio Vargas
Sent: Tuesday, October 26, 2010 3:04 PM
To: taxacom at mailman.nhm.ku.edu
Subject: Re: [Taxacom] Surprise from a whole-genome study



Hi,

>I admit to being very ignorant of the research basis for recognizing
lateral gene transfer. Out of curiosity, what is the evidence that a
genetic sequences is derived from another organism rather than
representing a convergent development?

gene structure I think, syntheny, different evolutionary rates (not sure
about this one), different codon-usage or nucleotide frequencies, etc.

sergio


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