[Taxacom] Felsenstein lecture available on-line

Dr. David Campbell amblema at bama.ua.edu
Fri Dec 5 16:19:03 CST 2008


> David Campbell wrote:
> "Aligning or at least checking alignments by hand is a valuable way
> to catch anomalous sequences, whereas feeding raw sequences into an
> analysis that internalizes the homology model makes anomalous
> sequences easy to overlook."
> 
> Are you referring here to POY?

POY is probably the most prominent example of what I was cautioning 
about.  Of course, you can look at the sequences and then feed them 
into POY, or even take a second look at anything that places oddly 
(especially if different genes are giving different results) after you 
run it, but I am aware of a few curious results that came out of POY 
due to bacterial or otherwise anomalous sequences that were supposed to 
be molluscan.  

-- 
Dr. David Campbell
425 Scientific Collections Building
Department of Biological Sciences
Biodiversity and Systematics
University of Alabama, Box 870345
Tuscaloosa AL 35487-0345  USA





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